NF

Necrotizing fasciitis, commonly termed “flesh-eating disease,” is a life-threatening bacterial infection characterized by rapid destruction of soft tissue, fascia, and subcutaneous layers.

NF is primarily caused by bacterial pathogens, most commonly Group A Streptococcus (e.g., S. pyogenes), though Vibrio vulnificus, Clostridium, Klebsiella, and polymicrobial infections are also implicated.

Risk factors include:

• Immunocompromised states (diabetes, cancer, liver/kidney disease)
• Obesity, alcoholism, or intravenous drug use
• Recent trauma, surgical wounds, or exposure to contaminated water/seafood