(L.A.) Annie Varghese, 40, Died from Natural Causes

Deaths, Local died unexpectedly, natural death 0

Case Number: 2022-09809

Los Angeles County is reporting the death of a 40-year-old female.

The coroner’s office has identified the woman as Annie Varghese and listed her race/ethnicity as Middle Eastern.

Manner of Death: Natural

Cause of Death: Congenital Adrenal Hyperplasia

RIP ANNIE VARGHESE (March 11, 1982 – September 15, 2022)

Formal pronouncement of death was made on Thursday at 6:49 a.m.

Congenital adrenal hyperplasia refers to a group of genetic disorders that affect the adrenal glands, a pair of walnut-sized organs above the kidneys.

openvaers.com/vaersapp/report.php?vaers_id=2018074

A 40-year-old female patient received bnt162b2 (BNT162B2), intramuscular, administered in arm right, administration date 13 Jul 2021 (Lot number: EW0198) at the age of 40 years as dose 1, single for covid-19 immunisation. Relevant medical history included: “COVID”, start date: Apr 2020 (unspecified if ongoing), notes: She had COVID in Apr 2020 and she does not want to get the Delta Variant; “seasonal allergies” (unspecified if ongoing), notes: she also took a Zyrtec which she takes daily for seasonal allergies; “Congenital Adrenal Hyperplasia” (unspecified if ongoing), notes: She was born with CAH, Congenital Adrenal Hyperplasia, which is a genetic disorder…

https://www.openvaers.com/vaersapp/reports.php?symptoms=cah&ov_textsearch=both&covid_only=Yes

Adrenal Crisis Associated With COVID-19 Vaccination in Patients With Adrenal Insufficiency
https://academic.oup.com/jcemcr/article/1/4/luad079/7242395

To date, 9 cases of adrenal crisis, including ours, associated with COVID-19 vaccination have been reported. Considering the high degree of adverse reactions to COVID-19 vaccination, administration of prophylactic stress dose of glucocorticoids is strongly recommended, particularly in patients with symptomatic adverse reactions, to protect them from adrenal crisis.

Increased mortality in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
https://pubmed.ncbi.nlm.nih.gov/25279502/

Adrenal Crisis Secondary to COVID-19 Vaccination in a Patient With Hypopituitarism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035659/

https://www.openvaers.com/vaersapp/reports.php?symptoms=adrenal&ov_textsearch=both&covid_only=Yes